Folate (Folic Acid)- Not Just For Your Prenatal Vitamin
We have known for a few decades that low folate can cause severe neurological (neural tube) defects for the unborn child. If you are pregnant, this is one of the most compelling reasons to take your prenatal vitamin faithfully. This review points out the importance of folate for many other reasons. I Have known for years that this B vitamin is critical to our bodies biochemistry. It is also important for most of us that we take it in the form of folinic acid. In addition to Vit D (virtually everyone is extremely deficient and our bodies do not make Vitamin D unless we get a large amount of sunlight exposure), and Vitamin C (an important anti-oxidant that helps our bodies get rid of toxins) I would recommend you consider either a B-complex that would include folinic acid, or take a separate folinic acid supplement. Since this is a water soluble vitamin, you will not need to worry about taking too much.
Systems Biology, Functional Medicine, and Folates
Jeffrey Bland, PhD, FACN, FACB
Human biology is often not as simple as it seems on the surface. This is certainly the case with folates and their relationship to disease prevention. During the decades from the 1960s through the 1980s, Smithells made the discovery that folic acid was important in the prevention of neural tube defects in babies,1 Butterworth made the observation that folic acid was important in the prevention of cervical dysplasia,2 and McCully reported that folic acid was an important nutrient for the prevention of atherosclerosis associated with elevated homocysteine.3 These 3 observations redefined the clinical importance of folate nutrition from that of a vitamin that was important in hematology for the prevention of anemia to a state of importance in many subspecialties of medicine from obstetrics and gynecology to neurology and cardiology. More recently, epidemiological evidence has associated low-folate diets with an increased risk of colorectal neoplasia and colorectal cancer.4