Initial Treatment of Diabetes- Metformin Confirmed Superior (study)
For those who are diagnosed with diabetes that has not yet reached the severity requiring insulin, Metformin (which you can learn more about Metformin here… ) seems to be a superior choice as the first drug to use.
Metformin has been approved and successfully used for adolescents with type-two diabetes and children over age 10 with obesity or as an adjunct for type-1 diabetes.
In the article “Initial therapy for diabetes mellitus” (read here… ) they compared Metformin to sufonylureas, thiazolidinediones and dipeptidyl peptidase 4 inhibitors. Despite guidelines (by the American Diabetes Association, the American College of Physicians, and the Agency for Healthcare Research and Quality) suggesting Metformin to be a drug of choice, 57.8% of individuals began diabetes treatment with Metformin. Doing so was associated with reduced needs for subsequent added medications without any increase in rates of hypoglycemia or other adverse events.
You can also read the article “Initial Choice of Oral Glucose-Lowering Medication for Diabetes Mellitus:” by clicking here…