Maternal Inflammation Triggers Increased Autism
We have known since the autopsy study by Vargas in 1995 (you can read that here… ) that autism children have inflammation in their brains. In the 2014 study “Maternal Inflammation contributes to brain overgrowth and Autism-Associated Behaviors through altered Redox signaling in Step and Progenitor cells,” we now have a mechanism explained.
This study showed that maternal inflammation increased NADPH oxidase (NOX)-P13K pathway signaling which increased neural stem and progenitor cells and forebrain microglia and resulted in autism associated behaviors in offspring.
So this is a lot of technical science. In practical terms, how can we use this information? Avoid triggers of inflammation. What are the major known triggers of inflammation?
- Gluten in your diet
- Casein (dairy)
- High glycemic index foods (flour, sugar)
- Aspartame (diet sodas, gum, NutraSweet, etc.)
- Trans fats (hydrogenated) and saturated fats (animal fats, etc.)
- Omega-6 fatty acids
- MSG (called “natural flavors” in packaged foods)
- Alcohol (tiny amounts can be protective)
- Vitamin D deficiency
So basically: Eat fruits, vegetables, and lean proteins, take more omega-3 fish oil and your vitamin D, and avoid the above list.