Heavy Metal Toxins
Complex NIH research study on heavy metal toxicity and the interaction between genes, our endocrine system, and metal toxicity. This study is packed with important, complex information.
Link to the article: http://ehp.niehs.nih.gov/2013/01/1205659/
Some key points:
1. Seven environmental metals were selected for inclusion in the computational analysis, namely arsenic, cadmium, chromium, lead, mercury, nickel and selenium.
2. The glucocorticoid receptor pathway was computationally predicted to be a key mediator of multiple metal-induced birth defects.
3. For each of the metals, a number of genes were identified with known relationship to Cd (n=518 genes), Cr (n=175 genes), Hg (n=334 genes), iAs (n=1880 genes), Ni (n=637 genes), Pb (n=774 genes), and Se (n=1616 genes).
4. Genes that were thus identified as both metal and development-associated, ranged in count from 76 to 604.
5. The Gonadotropin hormone pathway was predicted to mediate (toxicity eliminated) the (developmental-delay and toxic) response to the following metals Cd, Hg, iAs, and Se.
6. Low levels of iAs (ARSENIC) (0.1μM or 7.5 ppb) were shown to induce structural birth defects including microcephaly, anterior neural tube defects (anencephaly), and gross craniofacial defects (RECALL DRINKING WATER ALLOWS UP TO 10 PPB).
What this really means in simple language is that there are hundreds of genes that are known to make us more vulnerable to heavy metal toxins. Bottom line – we are all vulnerable to toxicity of heavy metals – so when you read and hear of another genetic link to this, that, and the other …. just roll your eyes …. then refocus on what we all need to do which is to avoid toxins every way we can. This article also impresses me regarding two very important points:
1. We are already living with excessive toxin loads and exposures.
2. Chronic health issues may largely be related to the interaction of toxins and how they suppress or damage our endocrine system.
The call to action here is to eat organic, avoid high arsenic foods like rice products, drink filtered low toxin water, avoid all foods in cans and commercially-prepared boxed and plastic-bottled or canned foods, and if you are having any health issues (immune, neurological, developmental, or otherwise) have a discussion with your physician about getting hormone levels checked. If checking your thyroid, make sure they include the free-T3 and TSH.